Skincare / AVEA SkinSpan Advanced Face Serum

AVEA SkinSpan Advanced Face Serum

Written by
Sophie Chabloz

AVEA’s SkinSpan™ Advanced Face Serum brings longevity science to your skin. It is AVEA’s only topical product, a serum that targets the four cellular drivers of skin ageing, NAD+ decline, slowed renewal, collagen and elastin loss, and a weakening barrier, rather than just hydrating the surface. In a finished-formula clinical study, visible wrinkles fell 31.7% and elasticity rose 29.6% in four weeks.

Why it is different

Most serums work on the surface. SkinSpan™ works on the biology underneath. Where typical longevity serums rely on a single mechanism, it acts on four: RejuveNAD sunflower-sprout extract raises the skin’s own NAD+ for cellular energy, Cellaigie, an AI-designed peptide, reactivates autophagy to renew cells, PhytoCellTec Exosomes from goji stem cells signal fibroblasts to rebuild collagen and elastin, and a barrier complex of niacinamide, Ectoin, beta-glucan, betaine and low-molecular-weight hyaluronic acid strengthens and hydrates. It is the topical counterpart to AVEA’s supplements: the same longevity mechanisms, applied to the skin.

What it helps with

  • Smoother skin with visibly reduced fine lines and wrinkles
  • Improved firmness and elasticity
  • Immediate hydration and a stronger skin barrier
  • Cellular energy and renewal for healthier-looking skin over time

Key ingredients

  • RejuveNAD (sunflower sprout extract) 2%, for skin NAD+
  • Niacinamide (vitamin B3) 3%, for the barrier
  • Cellaigie (acetyl tetrapeptide-2) 2%, for autophagy and renewal
  • PhytoCellTec Exosomes (goji stem cell) 0.4%, for collagen and elastin
  • Ectoin 2%, for environmental protection
  • Low-molecular-weight hyaluronic acid, betaine, beta-glucan and diglycerin, for hydration and barrier

How it works

The serum targets four drivers of skin ageing. Energy: RejuveNAD raises the skin’s own NAD+ by upregulating NAMPT, the enzyme that paces NAD+ production, restoring the cellular energy skin needs to repair. Renewal: Cellaigie reactivates autophagy, the skin’s cellular clean-up, to clear damaged proteins and speed renewal. Structure: PhytoCellTec Exosomes prompt fibroblasts to produce collagen III, collagen XVI and elastin for firmness. Barrier: niacinamide, Ectoin, beta-glucan, betaine and hyaluronic acid strengthen the barrier and lock in moisture. In a dermatologist-supervised finished-formula study (N=20, twice daily, 8 weeks), visible wrinkle counts fell 31.7% and elasticity rose 29.6% at four weeks, both sustained at eight weeks; skin moisture rose 21% and water loss fell 19.4% within 30 minutes of the first application, with zero adverse events. Results are averages and vary from person to person.

How to use

Apply one to two pumps to clean, damp skin twice daily, morning and evening. Press gently into the face, neck and decolletage until absorbed. Use before moisturiser or sunscreen in the day, and before night cream in the evening. One pump is enough for the whole face.

Works well with

Pair with the SkinSpan™ supplement for the complete inside-out SkinSpan™ System: the serum works on the skin while the supplement supports it from within. Add the Collagen Activator to supply the building blocks for the new collagen the serum signals for.

Good to know

Vegan and cruelty-free. Alcohol-free and fragrance-free, 89% of natural origin, with no parabens, PEGs, phthalates or phenoxyethanol. Developed and manufactured in Switzerland under GMP conditions, and dermatologically tested. Covered by AVEA’s 90-day money-back guarantee.

By

Sophie Chabloz

Sophie is the co-founder and Chief Science Officer at Avea, focusing on developing innovative supplements with an emphasis on ingredient synergies. She holds an MSc in Food Science, Nutrition & Health from ETH Zurich, underpinning her strong scientific and industry expertise.